What are SARMs?
Selective Androgen Receptor Modulators (SARMs) are a class of compounds developed through pharmaceutical research to investigate selective activation of androgen receptors in different tissues.
Non-steroidal SARMs emerged from androgen-receptor research during the 1990s, with compounds including Andarine (S4) and later Ostarine (MK-2866 / Enobosarm) forming part of the development of this research field.
SARMs have been investigated scientifically in areas including:
- Muscle-wasting conditions
- Osteoporosis and bone health
- Age-related loss of lean mass
- Androgen-receptor signalling
- Skeletal-muscle biology
- Tissue-selective androgen activity
The aim of SARM research has been to explore whether androgen-receptor activity can be selectively targeted in particular tissues while reducing some of the unwanted effects associated with traditional steroidal androgens. This remains an active area of pharmacological research.
Research Compounds
Compounds commonly discussed within SARM research include RAD-140, LGD-4033, MK-2866 and Andarine (S4). Each has its own chemical structure, pharmacological profile and area of research interest.
JW Supplements provides information about individual compounds and their relevant research categories on the corresponding product and educational pages.