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  • Ostarine is the SARM that is being developed for the prevention and treatment of muscle wasting.
It is currently undergoing clinical trials and may eventually be the medical prescription for prevention of cachexia, atrophy, and sarcopenia and for Hormone or Testoserone Replacement Therapy.

SARM MK-2866

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Product Description

Ostarine is the SARM that is being developed for the prevention and treatment of muscle wasting.
It is currently undergoing clinical trials and may eventually be the medical prescription for prevention of cachexia, atrophy, and sarcopenia and for Hormone or Testoserone Replacement Therapy.

84caps x 15mg Ostarine MK-2866

As a research chemical, Ostarine belongs to a class of chemicals known as SARMs or selective androgen receptor modulators. SARMs create selective anabolic activity at certain androgen receptors and not others, hence their name. Compared to testosterone and other anabolic steroids and pro hormones, the advantage of SARMs such as (Ostarine) MK-2688 is that they do not have androgenic activity in non-skeletal-muscle tissues.

Ostarine is effective in not only maintaining lean body mass (LBM) but actually increasing it.

It is often described or named S1 on various interenet sources, however this is actually incorrect as S1 was a SARM that was develped quite early and is no longer undergoing any further development.

How does it work?
Selective androgen receptor modulators (SARMs) bind to the androgen receptor and demonstrate osteo (bone) and myo (muscular) anabolic activity.

Androgen receptor activation
Binding and activation of the Androgen receptor alters the expression of genes and increases protein synthesis, hence builds muscle.

So in essence, SARMs such as Ostarine causes muscle growth in the same manner as steroids, however unlike testosterone and other anabolic steroids and prohormones, SARMs (as nonsteroidal agents) don’t produce the growth effect on prostate and other secondary sexual organs.

Ostarine in particular exerts its anabolic effects on muscle tissue almost exclusively. So not only does it represent a new potential treatment option for a wide spectrum of conditions from muscle wasting diseases (from age-related to AIDS or cancer-related), but is also has immense potential for muscle building for Bodybuilders, fitness, athletes and an agent to minimize atrophy during recovery periods from serious surgery or similar situations.

Evidence of Ostarine’s Abilities?
To date Ostarine has been evaluated in eight clinical trials involving approximately 600 subjects including three efficacy studies. A four month Phase IIb clinical trial enrolled 159 patients with the study meeting its primary objective of an absolute increase in total lean body mass (muscle) compared to placebo and the secondary objective of muscle function (increase in strength).

In particular application to bodybuilding, there have been many logs of users on various forums using Ostarine as an aid to increase lean body mass and strength levels.

Hence it is safe to say that if the 100% exact structure is not yet available, an extremley similar compound upwards of 99%+ is available. Hence for all intense purposes, the same compound of Ostarine or MK-2866 is infact available to purchase by researchers.

Uses of Ostarine
Lean muscle gains (bulking)
As Ostarine is the most anabolic of the available SARMs, its first and formost use must be when trying to gain lean muscle.

Now the gains in absolute weight won’t be comparable to steroids such as diannabol, however what will be gained will almost exclusivley be lean mass. Due to the lack of shutdown in comparison to steroids/prohormones, a PCT period is not needed and almost all the mass that is gained on Ostarine is kept once the cycle is finished.

Doses of 25mg for 4-6 weeks are the most common protocol for such goals. Over this 4-6 week period will typically produce 6lbs or 3kg of lean, keepable gains. However the abundant side effects of steroids/prohormones will not be present.

Users have as high as 36mg [only recommended for those who weigh in at 210lbs (95kg)+] for periods as long as 8 weeks. However the potential for suppression from such doses is higher and users would have to look into a PCT protocol after undergoing such a cycle.

As the majority of Ostarine supplies come in 30ml bottles at 25mg/ml, a dose of 17.5mg per day will give the user a 6 week cycle from one bottle, a very good compromise between an anabolic dose and cost.

Losing Bodyfat (cutting)
Ostarine would primarily fit into a cutting protocol for the maintainance of muscle mass whilst reducing calories.
One of the most disheartening outcomes of cutting is the loss hard earned muscle mass.
The drop in metabolic rate and hormone levels (T3, IGF, Testosterone etc) with the lack of calories is a perfect catabolic enviroment for loss of muscle tissue.
As Ostarine has anabolic effects, the dieter can cut calories without having to worry about muscle or strength loss.
Ostarine has also shown noticeable nutrient partioining effects among users, another reason why it can be of great help when cutting.

A 12.5-15mg dosing protocol for 4-6 weeks is good for cutting with Ostarine without undergoing any side effects or suppression.

However it must be stated that due to the lack of androgenicity, muscle hardness and overall results are not as prominenant as with the SARM S-4.

Recomping (gaining muscle and losing bodyfat at the same time)

In our opinion, along with lean gains in muscle mass, Recomping is where Ostarine really shines.

The recomping effect of losing fat and gaining muscle at the same time is what the majority of users are looking for. Trying to achieve this when you are not absolutely new to training is extremely difficult.

Where Ostarine shines for recomping is in its nutrient partioning benefits. Calories are taken from fat stores and calorie intake is fed to the muscle tissue. In fact many users report that Ostarine consumed at maintainace calories produces weight loss, whilst still getting increases in strength and muscle mass!

One of the most important factors of recomping is TIME. As you are trying to achieve multiple objectives, it requires a longer time period to notice good recomp effects so even when running steroids, these would have to be longer run injectible compounds as oppose to the short used liver toxic oral steroids/prohormones.

Although Ostarine is taken orally, as it is not methylated it is not as liver toxic as other oral steroids/prohormones. Therefore it can be run for longer than the standard 4 week period with the aforementioned compounds.

The dosing protocol of 12.5-25mg for 4-8 weeks will give excellent recomp effects.

Diet must also be optimized to where calories are just above maintaninance with at least 30% coming from lean sources of protein to get the best recomp effect.

Injury Prevention

As mentioned by Furuya, the effects of MK-2688 translate to anabolism in bone as well as skeletal muscle tissue, which means it could be used in the future for a wide variety of uses such as osteoporosis and as a concurrent treatment with drugs that reduce bone density.

Therefore it has great application as a compound to use for rehabilitation of injuries, in particular bone and tendon related injuries.

Doses of 12.5mg per day is recommend for such purposes and improvement in joint movement that can be seen after just 6-8 days.
Timing of Doses

As Ostarine has a half life of around 24 hours, each of these doeses only has to be taken orally once a day, therefore its also offers an extremely convientinet supplementation intake.
Ostarine and estrogen concern

SARMs cannot be aromatized, conferring all their effects to AR binding and not to metabolic conversion to active androgens/estrogens.

However blood work from users has shown a slight elevation in serum estradiol levels (which may be one of the factors in its high effectiveness for treating tendon, ligament, and bone injuries or illnesses.

This elevation is extremely small and is no case for concern. If however you are absolutely concerned about slight increases in Estrogen, you can always opt for low doses of OTC AI’s such as 6bromo or very very low doses of prescription AI’s like adex or aromasin.

Advantages Of Ostarine when compared to Steroids/Prohormones

There is no need for pre cycle supports such as Hawthorn berry.

There is no need for on cycle supports such as milk thistle for the liver, policosanol or RYR for cholesterol etc.

Some suppression may be present at doses of 25mg+ run for longer than 4 weeks, however a stringent PCT of prescription SERMs like Nolva or Clomid is not necessary.

High oral biovailabilty without significant damage to your liver as with oral steroids/prohormones.

Great sense of well being while on, (without the aggression which can often detrimentally impact users daily lifes).

No need for a long time period off between cycles; the recommended time of period for normal cycles would be Time on +PCT, so for a typical 6 week cycle and 4 week PCT, a user would have to wait another 10 weeks after PCT to start another cycle.

Ostarine (MK-2866) also resulted in a dose-dependent decrease in LDL and HDL cholesterol levels, with the average LDL/HDL ratio for all doses remaining in the low cardiovascular risk category – hence there is little impact on cholesterol values.

Advantages Of Ostarine when compared to other SARMs

    The metabolite M1 wich seems to cause toxicity in S4 (temporary occular disturbances) is not present in Ostarine.
    Also unlike S4, Ostarine does not have androgenic properties in non muscle tissue.
    Ostarine Summary
    Anabolic even at doses as low as 3mg
    Great for strength
    Great for lean mass gains
    Great for body recomposition
    Great for endurance (aerobic or anaerobic)
    Joint healing abilities
    Half life of circa 24 hours – only once a day dosing required

This product is by no means intended to diagnose, treat or cure any medical condition and are not to be considered a medicine.

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Product Reviews

Write your own product review

Showing reviews 1-10 of 26 | Next

  1. healing

    Posted by SERGIO CASTRO on 8th Mar 2018

    i fell more energy and focus in the workout, I think i star to get more muscle .

  2. just started these as well as mk677

    Posted by Unknown on 19th Jan 2018

    Taking one mk2866 and two of the mk 677 try to gain a bit more muscle and get ride of some fat , I’ll post again in 5 weeks time to say if it worked or not

  3. The Dosage is two high.

    Posted by Charlie on 18th Nov 2017

    The sweet spot is 20-25mg and with these capsules you can only have 15mg (too little) or 30mg (too much).

    EVERYBODY says 30mg is too much.

  4. Serious lean muscle gains

    Posted by Leighton Jones on 24th Jun 2017

    I was using testofuel (expensive at £40 a bottle with little benefit you have to run it for atleast 3 months to start seeing good results) so I decided to take the plunge and after two weeks of taking 2 capsules a day have started stacking it with cartarine again two capsules a day in 3 and a half weeks I have gained 4lbs and lost a good few inches around my stomach I haven't had a beer since New Year's Eve but after quite a few years having a few beers every night gained quite a bit of a beer belly that wasn't shifting until I started this stack my calorie intake is quite high about 3500/4000 calories a day as I have a fast metabolism but even using the cartarine I'm gaining lean muscle and loosing weight in the correct place. I will update full results after running both for 8 weeks... if continue with gains will look at running lgd elite as well ... train 5/6 days a week

  5. good stuff

    Posted by rinka on 7th Jun 2017

    my diete was 2200 calorie per day for get shreds and i take strenght and keep the muscle i think its not fake ostarine. but i have diareha with ostarine but this side effect is normal.
    People who complain because of the side effects if you dont want to do not take ostarine is not a food complement ...

  6. be careful

    Posted by shane on 14th May 2017

    It made me so ill. I had chronic stomach problems for weeks . It made me go to the toilet 40 times a day . It might just be my sensitive system. I eliminated every possible thing from my diet .. but nothing changed until I gave up mk2866- I was better in a few days. Terrible experience .
    I lost 2 stone. Never realised it was this supplement that was causing the problem as I buy a lot of varying things from JW which are very good. .

  7. Overall Great!

    Posted by John on 1st Apr 2017

    Preserved my muscles while was recovering from surgery. Wasn't able to train properly in 4 weeks. My cycle was 8 weeks total and 15mg day.

    Great pump at the gym. Endurance went up and kept muscles fuller all day. Didn't gave any significant strength gains. Didn't have any side effects. Can't say anything about suppression, because i am on TRT. However did full blood work after the cycle and everything was spot on. No elevated liver enzymes or cholesterol issues ether. I would say legit ostarine.

    One thing about JW. Their customer service has always been great. Super fast shipping. Multiple orders behind and i have been very satisfied. Thanks.

  8. Ostarine is a God send

    Posted by zPhysic on 10th Mar 2017

    Currently on a low macro cycle to cut fat ready for summer, as for low calories muscle loss is inevitable but with ostarine I've a managed to keep strength and minimise muscle loss to bare minimum. Great product always trust it, also a good bridging supplements

  9. ostarine is a genuine product

    Posted by Unknown on 10th Mar 2017

    Experienced moderate strength and size gains. Thought this was a fantastic product would use again. Just hope the science continues to prove this is safe as this is better than mild orals.

  10. Great Product

    Posted by Ian Hackett on 15th Jan 2017

    Tried Ostarine from another site previously, the one from JW supplements is a lot more potent. Am already seeing results lot more strength and energy and the weight is falling off.

Showing reviews 1-10 of 26 | Next

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